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Decoding Inborn Errors of Immunity:
From Molecular Roots to Therapeutic Frontiers

5 th April 2025 (08:30-17:30)
Yugoslav Film Archive, Uzun Mirkova Street 1, Belgrade, Serbia

Support from institutions, associations and organizations

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Gallery 2025

Greeting Message

Dear Colleagues, Esteemed Collaborators in the Field of Diagnosis and Treatment of Inborn Errors of Immunity, and Honored Guests,

It is with great pleasure that we announce the opening of registration for the First International Symposium of the Serbian Group for Primary Immunodeficiencies (SGPI 2025), titled:

“Decoding Inborn Errors of Immunity: From Molecular Roots to Therapeutic Frontiers”

The symposium will be held on Saturday, April 5, 2025, in Belgrade, at the Yugoslav Film Archive, Uzun Mirkova 1, commencing at 9:00 AM.

The SGPI 2025 Scientific Committee has developed a comprehensive and dynamic program encompassing a wide spectrum of Inborn Errors of Immunity (IEI)—ranging from hereditary disorders of innate and adaptive immunity (including humoral and combined immunodeficiencies) to immune dysregulation syndromes and autoinflammatory diseases.

With the participation of renowned experts from Serbia and abroad, SGPI 2025 will present state-of-the-art advancements in the field of IEI, covering cutting-edge diagnostic technologies, such as genetic analysis, as well as the latest therapeutic innovations, including targeted therapies and stem cell transplantation.

Organized in collaboration with Supporting Persons with Primary Immunodeficiency (SPwPID/POsPID), the symposium will also provide a dedicated forum for individuals living with IEI to engage in meaningful discussions regarding the challenges they encounter—spanning early symptoms, diagnosis, and long-term treatment management. A central aim of this event is to amplify the voices of patients and to foster collaborative efforts toward enhancing healthcare services, preventing complications, and improving overall quality of life.

We extend our sincere gratitude to the esteemed associations, institutions, and organizations that support SGPI 2025, including: European Society for Immunodeficiencies (ESID), International Patient Organization for Primary Immunodeficiencies (IPOPI), University Clinical Center of Serbia (UCCS), Mother and Child Health Care Institute of Serbia, Institute of Molecular Genetics and Genetic Engineering (IMGGE), Regional Medical Chamber of Belgrade (RMCB)

We eagerly anticipate your participation in SGPI 2025 and look forward to welcoming you to this prestigious scientific gathering.

Asst. Prof. Maja Stojanović
President of the Serbian Group for Primary Immunodeficiencies

SGPI 2025

The SGPI 2025 Symposium is a distinguished scientific and professional event dedicated to highlighting the critical importance of a multidisciplinary approach in the diagnosis and treatment of patients with congenital immune system disorders, collectively known as Inborn Errors of Immunity (IEI). This symposium serves as a platform for the exchange of knowledge and expertise through engaging discussions, while also fostering opportunities for professional networking with colleagues from both national and international institutions. A key objective of this gathering is to facilitate institutional and global collaboration in the field.

The exchange of knowledge, ideas, and clinical experiences is expected to contribute to advancing scientific understanding and increasing awareness of these highly complex immune disorders. The ultimate goal is to enhance professional expertise in the diagnosis and management of IEI, thereby improving patient outcomes and overall quality of life.

The SGPI 2025 Symposium is currently undergoing accreditation as an international scientific event. No registration fee is required for participation.

Due to the limited number of available places, prior registration is mandatory. Participants must complete the registration form provided below. Confirmation of registration and participation will be sent to the email address submitted during the registration process.

We invite all interested colleagues to submit scientific abstracts aligned with the symposium’s thematic focus areas, including: Congenital immune system disorders – primary immunodeficiencies, including hereditary angioedema and autoinflammatory disorders, Secondary immunodeficiencies.

Abstracts should be submitted via email to sgpid.registracija@gmail.com by February 25, 2025. Notifications regarding the selection of abstracts for presentation will be sent no later than March 20, 2025.

As part of the symposium program, a special award will be conferred for the most outstanding scientific contribution, to be presented during the SGPI 2025 Symposium.

For additional details or inquiries, please contact us via email at sgpid.registracija@gmail.com.

On behalf of the organizing committee of the SGPI 2025 Symposium:

  • Asst. Prof. Maja Stojanović, President of SGPI
  • Gordana Petrović, MD, PhD, Vice President of SGPI
  • Asst. Prof. Rada Mišković, Secretary of SGPI

Agenda SGPI POSPID Symposium

Download the program in PDF

Decoding Inborn Errors of Immunity: From Molecular Roots to Therapeutic Frontiers

5 th April 2025 (08:30-17:30) Yugoslav Film Archive, Uzun Mirkova Street 1, Belgrade, Serbia
Registration of participants from 08:30
Welcome by the organizers (SGPI/SPwPID) 08:50 – 09:00

Session 1 Multidisciplinary Approach to IEI (09:00-10:45)

Moderators: Prof. Branka Bonaci-Nikolić (UCCS, Serbia) and Prof. Desa Lilić (Newcastle University, UK)

  • 09:00-09:15 Prof. Branka Bonaci-Nikolić (UCCS, Serbia) – Spectrum of IEI: phenotype/genotype correlation
  • 09:15-09:30 Prof. Sonja Pavlović (IMGGI, Serbia) – The importance of genetic analysis in patients with IEI
  • 09:30-09:45 Asst. Prof. Maja Stojanović (UCCS, Serbia) – CVID and CVID-like disorders
  • 09:45-10:00 Prof. Goran Marjanović (UCC Nis, Serbia) – IEI and association with malignancies
  • 10:00-10:15 Ivan Ranković, MD, MSc, FRCP (Royal Cornwall Hospital, UK) – Gastroenterological approach to enteropathies in CVID
  • 10:15-10:25 Asst. Prof. Ana Petković (UCCS, Serbia) – Enteropathies in CVID from a radiological
    perspective: Our experience
  • Discussion and key takeaways by session moderators: 10:25-10:45

Coffee break: 10:45-11:00

Session 2 IEI in Paediatric Patients (11:00-12:15)

Moderators: Prof. Mario Abinun (Newcastle University, UK), Prof. Srdjan Pašić (IMCHC, Serbia), and Assoc. Prof. Borko Milanović (ICYHCV, Serbia)

  • 11:00-11:15 Martine Pergent (IPOPI President) & Maja Stojanović (SGPI) – Importance of networking and collaboration among patients and professionals – International perspective
  • 11:15-11:30 Želimir Erić, MD, MSc (UKC Banja Luka, RS) – SCID: Challenges in recognition and treatment
  • 11:30-11:45 Gordana Petrović, MD, PhD (IMCHC, Serbia) – The importance of neonatal screening for SCID
  • 11:45-12:00 Prof. Slađana Andrejević (UCCS, Serbia) – Agammaglobulinemia: Clinical phenotypes and management
  • Discussion and key takeaways by session moderators: 12:00-12:15

Coffee break: 12:15-12:25

Session 3 Hematopoetic Stem Cell Transplantation (HSCT) in IEI 12:25-13:05

Moderators: Prof. Mario Abinun (Newcastle University, UK), Prof. Milena Todorović-Balint (UCCS, Serbia), Prof. Dragana Vujić (IMC, Serbia)

  • 12:25-12:40 Prof. Dragana Vujić (IMC, Serbia) – HSCT in pediatric patients with IEI
  • 12:40-12:55 Prof. Milena Todorović-Balint (UCCS, Serbia) – HSCT in adult patients with IEI
  • Discussion and key takeaways by session moderators: 12:55-13:05

Session 4 Poster presentation 13:05-13:35

Moderators: Assoc. Prof. Borko Milanović (ICYHCV, Serbia), Asst. Prof. Radovan Mijanović (UCCS, Serbia) and Asst. Prof. Uros Karić (UCCS, Serbia)

  • Award Ceremony for the Best Poster Presentation (Assoc. Prof. Borko Milanović)

Session 5 Immune Dysregulations and Autoinflammatory Diseases (14:15-15:35)

Moderators: Prof. Goran Marjanović (UCC Niš, Serbia) and Prof. Slađana Andrejević (UCCS, Serbia)

  • 14:15-14:30 Prof. Tadej Avčin (UMC Ljubljana, Slovenia) – Overlap of primary and secondary immunodeficiencies
  • 14:30-14:45 Sara Bindoli, MD, PhD (Rheumatology Unit, University of Padova, Italy) – Adult-onset Still’s disease & Macrophage activation syndrome
  • 14:45-15:00 Asst. Prof. Rada Mišković (UCCS, Serbia) – Monogenic lupus and lupus-like syndromes
  • 15:00-15:15 Asst. Prof. Ivica Jeremić (Institute of Rheumatology, Serbia) – The spectrum of Behçet’s disease
  • 15:15-15:25 Asst. Prof. Dragana Lazarević (UCC Niš, Serbia) – Targeted therapy for IEI: Our experience
  • Discussion and key messages by the session moderators: 15:25-15:45

Coffee Break: 15:45-15:55 (SGPI, SPwPID)

Session 6 The Floor for the Patients and Patients’ Representatives (15:55-16:15)

Moderators: Natasa Gojković and Sandra Stojiljković Cvetković (SPwPID), and Asst. Prof. Maja Stojanović, Gordana Petrović MD PhD, and Asst. Prof. Rada Mišković (SGPI)

  • Current challenges of patients with IEI and potential improvements in diagnosis, treatment, and quality of life (A patient and family members sharing their journey from first symptoms to final diagnosis)

Session 7 Young Doctors’ Session (16:15-16.55)

Moderators: Jelena Ljubičić MD (UCCS, Serbia) – ESID Junior Country Representative and Youth Coordinator of SGPI, Aleksandra Dašić MD (UCCS, Serbia), Tijana Djerić MD (IMCHC, Serbia), Asst. Prof. Uroš Karić (UCCS, Serbia)

  • 16:15-16:30 Clara Franco Jarava, MD, PhD (Hospital Vall d’Hebron, Barcelona, Spain, Chair of the ESID Education Working Party) – Opportunities for Juniors in ESID
  • 16:30-16:45 Filippo Consonni MD (Ospedale Pediatrico Meyer, Florence, Italy) – ALPS case presentation
  • Discussion and key messages by session moderators: 16:45-16:55

17:00: Presentation of the Lilic-Abinun Foundation, University of Newcastle, Newcastle, UK

 

Desa Lilic and Mario Abinun
Fund for the Advancement of Clinical Immunology in Serbia

Lilić-Abinun Fondacija

Closing word from the organizers and conclusion of the congress (SGPI, SPwPID)

Paralel sessions/small room of Yugoslav Film Archive: SPwPID

Workshop 1 12:15-13:00 IEI in Serbia

Moderators: Natasa Gojković (SPwPID) and Gordana Petrović MD, PhD (SGPI)

  • 12:15-12:30 Martine Pergent (IPOPI) and Dragana Koruga (SPwPID) – The importance of international cooperation for the development and efficiency of national organizations – opportunities and challenges
  • 12:30-12:45 Assoc. Prof. Borko Milanović – Analysis of the current situation: assessment of the number of patients, analysis of available diagnostics and therapy in Serbia
  • 12:45-12:55 Living with PID in Serbia (video and patient testimonial)
  • 12:55-13:05 MoLEVSA Representative – Possibilities of overcoming administrative difficulties and recognizing the problems of persons with IEI
  • 13:05-13:15 Representative from NORDS – The role of the network of patient organizations for Rd (national, regional, global)
  • 13:15-13:30 Dr. Rada Mišković (SGPI) and Ljiljana Kljajević (SPwPID) – Cooperation of SGPI and SPwPID, definition of common goals and cooperation plan in the coming period

Lunch break: 13:30-14:15 (SGPI, SPwPID)

Workshop 2 12:15-13:00 Physicians and patients – Importance of Collaboration

Moderators: Ljiljana Dragojević Vujasin (SPwPID) and Andrea Djuretić MD (ICYHCV, Serbia)

  • 14:15-14:30 Professor Goran Čuturilo (UCH Tirsova, Serbia)– The importance of genetic analysis in patients with IEI and their family members, interpretation of results, prenatal diagnosis
  • 14:30-14:50 Representatives of SGPI and SPwPID – Importance of collaboration between PID patient/family and physician (positive clinical practices)
  • 14:50-15:05 Representatives of SGPI– Symposium conclusions: What is important for patients?
  • 15:05-15:30 Q&A

Coffee Break: 15:45-15:55 (SGPI, SPwPID)

Closing Remarks from the Organizers and Conclusion of the Congress (SGPI, SPwPID)

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Symposium

5th April 2025 (08:30-17:30) Yugoslav Film Archive, Uzun Mirkova Street 1, Belgrade, Serbia